Both MyISAM and InnoDB are database storage system and is widely used in MySQL.
MyISAM is a storage engine used as the default storage engine for MySQL database. MyISAM is based on the ISAM (Indexed Sequential Access Method) concept and offers fast data storage and retrieval. But it is not transaction safe.
InnoDB is a transaction safe storage engine developed by Innobase Oy and was acquired by Oracle in October 2005.